Professional Awards and Experience

Co-Associate Dean, Equity, Diversity and Inclusion (EDI), UNSW Science (July 2024 - April 2025)

Cancer Institute NSW Career Development Fellow 2022-2024

Associate Fellow (AFHEA) Advance Higher Education 2021

Bridge Program Industry Fellowship 2021

Cancer Institute NSW Early Career Fellow 2018-2021

Hope Funds for Cancer Research Postdoctoral Fellow (University of Virginia/UNSW) 2014-2017

Postdoctoral Research Associate, University of Virginia (USA) 2012-2014

Anthony Rothe Memorial Trust PhD Scholarship, Children’s Cancer Institute (UNSW) 2008-2012

Research Assistant, Children’s Cancer Institute (UNSW) 2005-2008

Methods Development Scientist, GroPep Bioreagents (Adelaide) 2003-2005

Bachelor of Biotechnology (Hons), Flinders University of South Australia 2003

Research 

Dr Byrne received her PhD from the Children's Cancer Institute (UNSW) for her research investigating the role of the cell cytoskeleton protein, stathmin, in neuroblastoma (Byrne et al. 2014, Oncogene). Dr Byrne trained as a postdoc at the University of Virginia (USA) where she investigated the relationship between obesity and liver and endometrial (uterine) cancers (Byrne et al. 2014, Cancer Research). She now leads an independent lab in the School of Biotechnology & Biomolecular Sciences (Faculty of Science) focused on developing novel treatment strategies for cancer.

Research Focus 1: Developing new anti-cancer molecules that target metabolism

Dr Byrne is working with Prof Kyle Hoehn (School of BABS, UNSW) to investigate the therapeutic potential of novel mitochondrial uncoupler molecules in obesity and cancer. She is collaborating with Prof Naresh Kumar (School of Chemistry, UNSW) to develop novel small molecules that alter glucose metabolism in cancer cells.

Research Focus 2: Unravelling the links between obesity and cancer

Dr Byrne's lab is investigating how obesity promotes the development of cancer, specifically liver and uterine (endometrial) cancers. Her team have identified 'cancer-specific signatures' in obesity-related uterine cancer including changes in uterine microbiota (Kaakoush et al. 2022, Cancers), the transcriptome (Tanaka et al. 2022, Int J Mol Sci), circular RNAs (Tanaka et al. 2023, Gene) and the lipidome.

Teaching

Dr Byrne is an Associate Fellow of Advance Higher Education (AFHEA). She lectures in BABS3151 (topic: Cancer Genetics), BIOC3271/3671 (topic: Molecular Approaches to Cancer Cell Biology, Human Cytoskeleton and Disease), BIOC3261 (topic: Cancer Metabolism), and co-convenes BABS2011 (Current Trends in Biotechnology). She lectures and leads practicals in the School of Medicine (MFAC1525: Ageing and Endings). She supervises PhD, Masters, honours, and undergraduate students in the Schools of BABS, Chemistry, and Biomedical Sciences. 

Organisational roles

Chair: School of Biotechnology & Biomolecular Sciences Equity, Diversity and Inclusion (EDI) Committee (UNSW) 2022- current

School representative: Faculty of Science EDI working group (SEDIWG) 2022- current

Co-chair: Executive Committee for the Women in Research Network (WiRN) 2022-2023

Engagement with community

Dr Byrne recognizes the importance of communicating her research with research advocates, including Mr Jeff Cuff, who has been an active member of her laboratory since 2017 which led to co-authorship on Dr Byrne’s publication (Byrne et al, 2020 Redox Biology). She was interviewed by Leah Hazard, an NHS midwife and best-selling author, for her new book ‘Womb: The Inside Story of Where We All Began’. In this book Dr Byrne highlights her research on the link between disruption of uterine microbiota and uterine cancer.

Engagement with Industry

As a previous participant in the MTP Connect Bridge Program (2020) and prior recipient of a Bridge Industry Fellowship (2021), Dr Byrne now serves as the UNSW representative on the steering committee for the national drug commercialisation training program (Bridge Program).

Contribution to Profession

Dr Byrne reviews fellowship applications (Hope Funds for Cancer Research), NHMRC grants, HDR student theses, and manuscripts for Cancer Research, Molecular Cancer Research, Nature Communications, Gynecologic Oncology, Genes & Diseases, Cellular & Molecular Life Sciences, BMC, Cancers, AJP Endocrinology & Metabolism, etc.

She serves on the Honours Committee for the School of BABS and helps organise and chair sessions at national conferences.

She is an invited Guest Editor for Cancers (special issue: Mitochondrial Uncoupling and Cancer).